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Mutation in human population
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MUTATION IN HUMANPOPULATION
PRESENTED BY:- SAIFI MOHD IMRAN
BATCH:-191 A
GUIDED BY:- ANA ZHUKOVA
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What is human population:Human population refers to the number of people living in aparticular area, from a village to the world as a whole. A secondary
meaning of population is the inhabitants themselves, but in most uses
population means numbers.
No one knows the population of the earliest humans, but there may
have been only a few tens of thousands of individuals when the
species Homo sapiens first emerged 200,000 years ago. Today more
than 6 billion human beings inhabit the earth. Three-fifths of them live
in one continent, Asia, with the rest occupying every continent
except Antarctica.
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Age Structure, Population Growth, and EconomicDevelopment:The age structure of a population is an important factor in
population dynamics. Age structure is the proportion of a
population in different age classes. Models that incorporate age
structure allow better prediction of population growth, plus the
ability to associate this growth with the level of economic
development in a region. Countries with rapid growth have a
pyramidal shape in their age structure diagrams, showing a
preponderance of younger individuals, many of whom are of
reproductive age
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DNA is a remarkably precise medium for copying and storingbiological information. This high fidelity results from the
action of hundreds of genes involved in replication,
proofreading, and damage repair. Evolutionary theory
suggests that in such a system, selection has limited ability to
remove genetic variants that change mutation rates by small
amounts or in specific sequence contexts. Consistent with
this, using SNV variation as a proxy for mutational input, we
report here that mutational spectra differ substantially
among species