Thrombosis and Hemostasis Physiology

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THROMBOSIS AND HEMOSTASIS
PHYSIOLOGY
Dr Tzoran Inna
Thrombosis and Hemostasis Unit
Rambam Medical Center

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T-PA (TISSUE PLASMINOGEN ACTIVATOR)
U-PA (UROKINASE PLASMINOGEN ACTIVATOR)
PAI-1 (PLASMINOGEN ACTIVATOR INHIBITOR 1)
PAI-2 (PLASMINOGEN ACTIVATOR INHIBITOR 2)
Α2-AP (Α2-ANTI PLASMIN

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TAFI (thrombin
activatable
fibrinolysis
inhibitor)

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COAGULATION INHIBITORS

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Anti Thrombin inhibitor
Inhibition of Factor VIIa by TFPI