Non-Sporeforming. Anaerobes

1.

2.

Non-Sporeforming
Anaerobes

3.

Non-Sporeforming
Anaerobes
Stains gram-variable or gram-negative,
but not a gram-negative cell wall

4.

Non-Sporeforming
Anaerobes (cont.)

5.

Most Common
Sites of Anaerobic
Infection

6.

Characteristics of
Anaerobic Infection

7.

Characteristic Clinical Signs of
Anaerobic Infection

8.

9.

Anaerobic Gram-Positive
Non-Sporeforming
Bacterial Infections

10.

Gram-Positive
Non-sporeforming
Anaerobes
NOTE:
Figure legend in text
indicates that each of these
organisms is a bacillus (i.e., rodshaped). This is INCORRECT.
Peptostreptococcus is, as the
name indicates, a coccus.

11.

Diseases Associated with
Anaerobic Gram-Positive Bacilli

12.

Gram Stain and Macroscopic
Colonies of Actinomyces
NOTE:
Molar tooth appearance
of colonies on agar can help
remind us that the oral cavity is a
common niche for Actinomyces.

13.

Actinomyces Infections

14.

Cervicofacial Actinomycosis
NOTE:
Sinus tract originating in oral cavity has
made it’s way to the surface at the jawline.

15.

Colonized IUD Resulting in
Pelvic Actinomycosis

16.

Epidemiology
of
Actinomycosis

17.

Sulfur Granule from Sinus Tract of
Actinomycotic Infection

18.

Epidemiology of
Propionibacterium
(doxycycline)

19.

20.

Anaerobic Gram-Negative
Non-Sporeforming
Bacterial Infections

21.

Anaerobic Gram-Negative Infections

22.

Anaerobic Gram-Negative Infections (cont.)

23.

Clinically Predominant Anaerobic Gram-Negatives

24.

Broad Classes of Virulence Factors
Associated with Gram-Neg. Anaerobes
Adhesins
Protection from:
• Oxygen toxicity
• Phagocytosis
Tissue Destruction

25.

Anaerobic Gram-Neg. Virulence Factors

26.

Anaerobic Gram-Negative Virulence
Factors (cont.)

27.

Epidemiology of
Bacteroides

28.

Bacteroides Gram Stain

29.

Bacteroides Virulence Factors

30.

MIXED
Bacteroides
Pathogenicity
[1]
MIXED
[5]
MIXED
[3]
LIVE
[4]
LIVE
[2]
DEAD
[6]
SUBUNIT
[8]
SUBUNIT
[7]
+
+

31.

32.

REVIEW
Non-Sporeforming Anaerobes

33.

Characteristics of
Anaerobic Infection
REVIEW

34.

Characteristic Clinical Signs of
Anaerobic Infection
REVIEW

35.

Most Common
Sites of Anaerobic
Infection
REVIEW

36.

37.

Review of
Anaerobic Gram-Positive
Non-Sporeforming
Bacterial Infections
REVIEW

38.

Gram-Positive
Non-sporeforming
Anaerobes
REVIEW

39.

Actinomyces Infections
REVIEW

40.

Epidemiology
of
Actinomycosis
REVIEW

41.

Epidemiology of
Propionibacterium
(doxycycline)
REVIEW

42.

43.

Review of
Anaerobic Gram-Negative
Non-Sporeforming
Bacterial Infections
REVIEW

44.

Anaerobic Gram-Negative Infections
REVIEW

45.

Anaerobic Gram-Negative Infections (cont.)
REVIEW

46.

Clinically Predominant Anaerobic Gram-Negatives
REVIEW

47.

Broad Classes of Virulence Factors
Associated with Gram-Neg. Anaerobes
Adhesins
Protection from:
• Oxygen toxicity
• Phagocytosis
Tissue Destruction
REVIEW

48.

Anaerobic Gram-Neg. Virulence Factors
REVIEW

49.

Anaerobic Gram-Negative Virulence
Factors (cont.)
REVIEW

50.

Epidemiology of
Bacteroides
REVIEW

51.

Bacteroides Virulence Factors
REVIEW

52.

MIXED
Bacteroides
Pathogenicity
MIXED
[5]
MIXED
[3]
LIVE
[4]
LIVE
[2]
DEAD
[6]
SUBUNIT
[8]
SUBUNIT
[7]
+
+
REVIEW
[1]