Total Syntheses of Trichorabdal A and Maoecrystal Z
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Categories: medicinemedicine chemistrychemistry
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Total Syntheses of Trichorabdal A and Maoecrystal Z

1. Total Syntheses of Trichorabdal A and Maoecrystal Z

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Scheme 1. Retrosynthetic analysis on maoecrystal Z (1) and trichorabdal A (2).
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Scheme 2. Rapid construction of 13 via cross-ring radical cyclization.
Scheme 3. Attempts on the formation of 17.
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Scheme 5. Synthesis of the advanced intermediate 38.
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Scheme 7. Two chair conformations in the ring A of trichorabdal A (2).
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